Linchuan Liao Ph.D

Professor / Doctoral supervisor

Head of Department of Forensic Toxicological Analysis

Sichuan University

Address:

West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, Sichuan 610041,China

Phone number: 86-28-5501636

Fax Number: 86-28-85501636

Email Address: linchuanliao@scu.edu.cn

Prof. Liao conducts teaching tasks ofForensic Analytical Toxicology, Forensic Medicineand etc. for undergraduate students, oversea students, and postgraduate students at various levels. He is responsible teacher of the course“Forensic Toxicological Analysis”.With his effort, it was selected as the national classic course and the national high-quality resource sharing course. His academic interests focus on establishing determination methods related with toxicant as well as their metabolic process, pharmacokinetics and distributions. And his main research interests lie in abused substance. His research program is to exploit the metabolic process, body distribution, addiction mechanism of abused substance. He was the pioneer who involved metabonomics into the research on addiction mechanism. He is undertaking many projects including National Science and Technology Support Program, National Natural Science Foundation of China, CMB fund, etc. The ongoing research is “The metabonomics study on metabolic characteristics and the mechanism of toxicity induced by ketamine.”

He has published more than 80 research and educational reform papers, in which there are about 80 papers indexed by SCI or EI. He has cultivated and has been training more than 50 postgraduate students.

He is vice chairman of Toxicological Analysis committee of Chinese forensic society; Deputy Director of drug and toxicological analysis professional committee of Forensic Science Association of China; Editorial board member ofJournal of Forensic Science, Chinese Journal of Forensic Medicine, Journal of Forensic Science and Medicine. He is also one of the head of academic technology in Sichuan province. And he is the expert of excellence with outstanding contribution of Sichuan Province.

Education and Training:

● School of Pharmacy, West China University of Medical Sciences, Chengdu, China, Bachelor, Pharmacy 1981~1986

● School of Forensic medicine, West China University of Medical Sciences, Chengdu, China, Ph.D, Pharmaceutical Analysis, Forensic Analytical Toxicology,1994~1997,

● School of Medicine, HongKong University, Postdo. research fellow, Toxicology, 2001~2002

Area of Interest:

Establishing the method of toxicant analysis; metabolic process; body distribution, addiction mechanism; metabonomics.

Selected Publication：

●Book:

1. Linchuan Liao, ”Forensic Medicine” ,People’s Medical Publishing House Press, 2017. National programming Textbook .(contributer )

2. Linchuan Liao, “Forensic Toxicological Analysis”, third，forth and fifth edition, People’s Public Health Press, 2004, 2009 and 2016.(chief editor)

3. Linchuan Liao, “Practical Forensic Medicine-VII Forensic Toxicological Analysis” , SciencePress, 2012.(chief editor)

4. Linchuan Liao, “The Practice of Drug Determination”, Law Press, 2011.(vice editor)

5. Linchuan Liao, “Practice guide Forensic Toxicological Analysis”, People’s Public Health Press, 2008. National programming Textbook(chief editor)

6. Linchuan Liao, “Forensic Toxicological Analysis”, High Education Press, 2006. National programming Textbook(chief editor)

7. Linchuan Liao, “Forensic Medicine”, High Education Press.2004. National programming Textbook(contributer )

● Article:

1. Lu C, Dong L, Zhou H, Li Q, Huang G, Bai SJ, Liao L*. G-Protein-Coupled Receptor Gpr17 Regulates Oligodendrocyte Differentiation in Response to Lysolecithin-Induced Demyelination[J].Scientific Reports, 2018, 8. SCI 4.259

2. 2. Wu Z, Chen F, Wu H, Liao L*, et al. Urinary metabonomics of rats with ketamine-induced cystitis using GC-MS spectroscopy[J].Int J Clin Exp Pathol, 2018, 11(2): 558-567. SCI 1.706

3. Huang X, Wang C, Sun J, Luo J, You J, Liao L, Li M. Clinical value of CagA, c-Met, PI3K and Beclin-1 expressed in gastric cancer and their association with prognosis[J].Oncology Letters, 2018, 15(1):947. SCI 1.390

4. Wang C Q, Ye Y, Chen F, Han W C, Sun J M, Lu X, Guo R, Cao K, Zheng M J, Liao L C*. Posttraumatic administration of a sub-anesthetic dose of ketamine exerts neuroprotection via attenuating inflammation and autophagy [J].Neuroscience,2017, 343: 30-38. SCI 3.277

5. Wu Z, Lu X, Chen F, Dai X, Ye Y, Yan Y, Liao L*. Estimation of early postmortem interval in rats by GC-MS-based metabolomics[J].Legal Medicine, 2017, 31:42. SCI 1.276

6. Chen J, Wei Q, Chen F, Wu H, Fu Y, Wu Z, Dai X, Ye Y,Yan Y, Liao L*. Determination of periplocymarin in human blood and urine by high performance liquid chromatography-mass Spectrometry.J Forensic Sci Med2017;3:191-6.

7. Dai X, Fan F, Ye Y, Chen F, Wu Z, Lu X, Wei Q, Chen J, Yan Y, Liao L*. Determination of Chlorpyrifos in Human Blood by Gas Chromatography-Mass Spectrometry[J]J Forensic Sci Med, 2017, 3(1):22.

8. Ye Yi, Fan Chen, Hao Wu, Haibo Luo,Liao linchuan*.Genetics Supplement Series The confirmation of genetic variants associated with the subjective response after alcohol consumption [J].Forensic Science International, 2017, 9SCI IF: 3.86

9. Buyi Xu, Yi Ye,Linchuan Liao*.Rapid and simple analysis of amphetamine-type illegal drugs using excitation– emission matrixfluorescence coupled with parallel factor analysis [J]Forensic Sciences Research, 2017, 25 July 2017:1-9

10. Xiang Lu, Qunxing Tang, Yi Ye, Run Guo, Fan Chen, Xinhua Dai, Youyi Yan,Linchuan Liao*. A Preliminary Urinary Metabolomics Study of Sprague–Dawley Rats after Short-term Ketamine Administration by Proton Nuclear Magnetic Resonance Spectroscopy [J]Journal of Forensic Science and Medicine, v.2, no.2, 2016 April-June, p.91

11. Gou R, Tang QX, Ye Y, Lu X, Chen F, Dai XH, Yan YY,Liao LC*.Effects of gender on ketamine-induced conditioned placed preference and urine metabonomics [J].Regulatory Toxicology and Pharmacology, 2016, 77: 263-274SCI IF:2.221

12. Ye Y, Yan YY, Gong DY, Gou R, Yang L,Liao LC*.Homicidal Poisoning in China Using Several Anesthetic Drugs [J].Journal of Forensic Sciences, 2016, 61(3):864-866SCI IF:1.127

13. Xu B Y, Ye Y,Liao L C*.Detection of Methamphetamine and Morphine in Urine and Saliva Using Excitation–Emission Matrix Fluorescence and a Second-Order Calibration Algorithm[J].Journal of Applied Spectroscopy, 2016:1-9.

14. Wang C, Zhou Y, Ruan R,Liao L, et al. High expression of COUP-TF II cooperated with negative Smad4 expression predicts poor prognosis in patients with colorectal cancer [J].International journal of clinical and experimental pathology, 2015, 8(6): 7112.SCI IF: 2.168